Anti-Rat C4 Polyclonal Antibody-10 mg (CAT#: CB-P546-K) Datasheet

Antibody

The polyclonal antibody reacts with rat C4. Rat complement factor C4 (formerly known as Gg protein) is composed of α, β and γ chains. The classical pathway of complement and the lectin activation pathway of mannose binding converge at C4. C1, MASP-1 and MASP-2 cleave C4, resulting in the formation of C4a and C4b. The latter can be cleaved to produce C4c and C4d, and all functional sites are lost in this step.