Cathepsin E Activity Assay Kit (Fluorometric) (CAT#: CB-P230-K) Datasheet

Kit

Cathepsin E (CTSE, EC: 3.4.23.34) is a gastric aspartyl protease that can act as a homodimer connected by disulfide bonds. This protease has a specificity similar to pepsin A and cathepsin D. It is an intracellular protease with the highest concentration on the surface of gastric epithelial mucus producing cells. It is the first aspartic protease expressed in the fetal stomach and is found in more than half of gastric cancers. Creative Biolabs' cathepsin E activity assay kit utilizes the ability of active cathepsin E to cleave MCA-based synthetic peptide substrates to release free MCA, which can be easily quantified using a fluorometer or Fluorometric microplate reader. The assay kit is simple and rapid, and can detect cathepsin E activity as low as 1 mU in biological samples.