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Anti-Mouse CD46 Monoclonal Antibody (clone MM10) -10 mg (CAT#: CB-P518-K) Datasheet

Product Type
Antibody
Description
The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46. MCP is a type I membrane glycoprotein consisting of four isoforms, namely two CD isoforms (51-58 kDa) and two BC isoforms (59-68 kDa), which are passed through a single CD46 Generated by alternative splicing of genes. Membrane cofactor protein is expressed in all cells and tissues except red blood cells. Membrane cofactor proteins are used to down-regulate complement activation on host tissues. MCP is a cofactor for factor 1 mediated cleavage of C3b and C4b. This method can protect host cells from autologous attack. MCP is a receptor for a variety of pathogens, including measles virus, streptococcus pyogenes and pathogenic Neisseria.
Size
100 µg
Cross reactivity
Rat

All products and services are for Research Use Only. Do Not use in humans.

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Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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