Product Type
Antibody
Description
Human anaphylatoxin C5a is a 74-residue glycopolypeptide, which is produced by proteolytic cleavage of complement factor C5 during complement activation. It can be proved that the various biological effects caused by C5a make it take granulocytes and macrophages as the main target cells and become important mediators of inflammation. All cellular responses to C5a are mediated through interaction with membrane-bound C5a receptors, which are seven transmembrane GTP-binding protein-coupled receptors of the rhodopsin supergene family. The C5a receptor is approximately 45 kDa.
Disease
Infectious diseases, Nephrology
Size
100 µg
Species
Human
Clonality
Monoclonal
Clone Number
W17/1
Buffer
PBS, containing 0.1% bovine serum albumin and 0.02 % sodium azide.
Application
Flow cytometry, Frozen sections, Paraffin sections
Application Notes
For immunohistology and flow cytometry, the diluent to be used depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution. The typical initial working dilution is 1:10.
Storage Instructions
Product should be stored at 4°C. Under recommended storage conditions, product is stable for at least one year.
Alternative Names
C5aR; CD88; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin receptor; C5a ligand; C5a-R; complement component 5a receptor 1
