Sialic Acid Assay Kit (Colorimetric/Fluorometric) (CAT#: CB-P247-K) Datasheet

Kit

Sialic acid is the general term for nine kinds of carbonate sugars with N or O substituted derivatives. The most common member of these sugars is N-acetylneuraminic acid (NANA). Sialic acid is widely distributed throughout mammalian tissues and Body fluids, including serum. Sialyl oligosaccharides have shown antiviral properties and are known to affect blood clotting and cholesterol levels. The level of sialic acid in body fluids is also an important marker for the diagnosis of cancer. A simple and direct method to measure the concentration of sialic acid Can be widely used in research and drug discovery.
Creative Biolabs' sialic acid assay uses a modified Warren method, in which sialic acid is oxidized to formylpyruvate and reacted with thiobarbituric acid to form a pink product. The color intensity at 549 nm or the Fluorometric intensity at Ex / Em = 555/585 nm is directly proportional to the concentration of sialic acid in the sample.