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CytoTox™ Complement System Classical Pathway Assay Kit (CAT#: CB-P209-K) Datasheet

Product Type
Kit
Description
The CytoTox™ Complement System Classical Pathway is an immunoassay for the qualitative and/or semi-quantitative assay of functional classical complement pathway and assay of complement deficiencies in human serum.

The CytoTox™ Complement Classical Pathway assay combines the specific activation of the pathway with the use of labeled antibodies specific for a neoepitope of the terminal complement complex, C5b-9, produced as the result of complement activation. Objective quantification of the activity of the classical pathway is valuable in a number of different clinical situations. The amount of complement activation can be expressed either in a qualitative way relative the value of a positive control or in a semi-quantitative way using a calibrator curve derived from a separate lyophilized activity control.
Size
96 wells

Figure 1 CP Qualitative application.

Table 1.

Table 2 Sera with known complement deficiencies were tested in the assay and the following results were obtained.


Table 3. Inter-assay precision was determined by testing three samples in duplicate. Results were obtained for six different runs.

Table 4. Intra-assay precision for qualitative application was determined by testing one sample in 40 wells.

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All products and services are for Research Use Only. Do Not use in humans.

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