CytoTox™ Complement System Classical Pathway Assay Kit (CAT#: CB-P209-K) Datasheet

Kit

The CytoTox™ Complement System Classical Pathway is an immunoassay for the qualitative and/or semi-quantitative assay of functional classical complement pathway and assay of complement deficiencies in human serum.

The CytoTox™ Complement Classical Pathway assay combines the specific activation of the pathway with the use of labeled antibodies specific for a neoepitope of the terminal complement complex, C5b-9, produced as the result of complement activation. Objective quantification of the activity of the classical pathway is valuable in a number of different clinical situations. The amount of complement activation can be expressed either in a qualitative way relative the value of a positive control or in a semi-quantitative way using a calibrator curve derived from a separate lyophilized activity control.