Product Type
Fc Silent Antibody
Description
Anti-Mouse CTLA-4-Fc silent antibody is derived from clone HB20.3 FQQ-YTE, which is a Mouse monoclonal antibody targeting the CTLA-4. And it is intended for the research of Metastatic melanoma.
Research Area
Cell Biology, Immunology
Antigen Distribution
Biased expression in lymph node (RPKM 10.3), appendix (RPKM 9.7) and 8 other tissues.
Disease
Metastatic melanoma
Size
100 ug
Immunogen
Recombinant Mouse CTLA-4 protein
Species
Mouse
Clonality
Monoclonal
Clone Number
HB20.3 FQQ-YTE
Conjugation
Unconjugated
Source
Recombinant
Buffer
PBS, pH 7.4
Application
Block
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Cytotoxic T-lymphocyte protein 4
Full Name
Cytotoxic T-lymphocyte protein 4
Background
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), also known as CD152, is a protein receptor and an immunogenic checkpoint that functions as a down-regulator of immune system responses. The gene responsible for encoding this protein is found on chromosome 2 in humans.
Alternative Names
Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD antigen CD152
Gene ID
12477
Uniprot ID
P09793
