Description
Anti-Mouse CTLA-4-Fc silent antibody is derived from clone 9D9, which is a Mouse monoclonal antibody targeting the CTLA-4. And it is intended for the research of Metastatic melanoma.
Research Area
Cell Biology, Immunology,
Antigen Distribution
Biased expression in thymus adult (RPKM 1.4), spleen adult (RPKM 0.8) and 6 other tissues
Disease
Metastatic melanoma
Immunogen
Recombinant Mouse CTLA-4 protein
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Cytotoxic T-lymphocyte protein 4
Full Name
Cytotoxic T-lymphocyte protein 4
Background
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), also known as CD152, is a protein receptor and an immunogenic checkpoint that functions as a down-regulator of immune system responses. The gene responsible for encoding this protein is found on chromosome 2 in humans.
Alternative Names
Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD antigen CD152
