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Fc Engineered Anti-Human IL23 Antibody, CDC-Enhanced (CAT#: BioBet-C014ZP) Datasheet

Target
IL23
Isotype
Whole Humanized Antibody
Description
Fc Engineered Anti-Human IL23 Antibody, CDC-Enhanced (BioBet-C014ZP) is a recombinant monoclonal Whole Humanized antibody against IL23. This product is a CDC enhanced antibody produced by our proprietary platform.
Indication
Moderate-severe plaque psoriasis
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Tildrakizumab. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
IL23A
Full Name
interleukin 23 subunit alpha
Background
This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
Gene ID
UniProt ID
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
Humanized IgG1
Indication
Moderate-severe plaque psoriasis

Moderate-severe plaque psoriasis
Autoimmune diseases
Moderate-severe plaque psoriasis

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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