Description
Fc Engineered Anti-Human CD20 Antibody, CDC-Enhanced (BioBet-C029ZP) is a recombinant monoclonal Whole Murine IgG1 antibody against CD20. This product is a CDC enhanced antibody produced by our proprietary platform.
Indication
Chronic lymphocytic leukemia; follicular lymphoma; some types of non-Hodgkin lymphoma (NHL);some non-cancer related illnesses
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced rituximab. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
MS4A1
Full Name
membrane spanning 4-domains A1
Background
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
Gene ID
931
UniProt ID
P11836
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
Murine IgG1
Indication
Follicular Non-Hodgkin's Lymphoma
Follicular Non-Hodgkin's Lymphoma Refractory
Follicular Non-Hodgkin's Lymphoma
Follicular Non-Hodgkin's Lymphoma Refractory
Blood cancers
Follicular Non-Hodgkin's Lymphoma
Follicular Non-Hodgkin's Lymphoma Refractory
