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Anti-Tissue factor Antibody, ADCC Enchanced (BioBet-CB-055LX) (CAT#: BioBet-CB-055LX) Datasheet

Target
Tissue factor
Isotype
IgG1
Description
Anti-Tissue factor Antibody, ADCC Enchanced (BioBet-CB-055LX) is a glycosylation-modified anti-Tissue factor therapeutic antibody.
Antibody Indication
Chronic lymphocytic leukemia; follicular lymphoma; some types of non-Hodgkin lymphoma (NHL);some non-cancer related illnesses
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Tissue factor antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TF
Full Name
Tissue Factor
Background
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Alternative Names
F3; coagulation factor III (thromboplastin; tissue factor); TF; TFA; CD142; tissue factor;
Gene ID
2152
UniProt ID
P13726
Field of research
Cell Biology, Immunology,
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1
Antibody Clone
BioBet-CB-055LX
Host
Human
Species Reactivity
Human
Description
ADCC-Enhanced Anti-Human Tissue factor (Marstacimab) Antibody is derived from clone Marstacimab, which is a Human monoclonal antibody with enhanced ADCC activity. Antibody-dependent cellular cytotoxicity (ADCC) is an important function of antibody. It is a part of the humoral immune response to limit and contain infection. The antibody targets the Tissue factor, and it is intended for the research of Hemophilia A.
Antibody Indication
Hemophilia A

Hemophilia A

Related Products

Anti-Tissue Factor Antibody, Non-Fucosylated (MORAb-066) (CAT#: BioBet-854ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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