Product Type
Antibody
Description
The polyclonal antibody reacts with rat C3. Complement factor C3 is composed of α chain and β chain. C3 is the core factor of the complement cascade. It is the key to the alternative pathway leading to the C3 convertase C3bBb. The classic lectin-activated pathway combined with mannose leads to the C3 convertase C4b2a. These invertases cleave C3 to produce C3a and C3b. Further degradation leads to the formation of alpha chain products C3d, C3g and C3c. C3 is an acute phase protein produced by a variety of tissues including kidney epithelial cells and liver cells.
Disease
Pulmonology
Size
100 µg
Species
Rat
Clonality
Polyclonal
Buffer
PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide
Application
Immuno assays, Western blot
Application Notes
For Western blots and immunoassays, the diluent used depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution. The typical initial working dilution is 1:50.
Storage Instructions
Product should be stored at 4°C. Under recommended storage conditions, product is stable for at least one year.
Alternative Names
Complement component 3
