Book a Meeting

Anti-MCSP Antibody, Non-Fucosylated (BioBet-1719ZP) (CAT#: BioBet-1719ZP) Datasheet

Target
MCSP
Isotype
IgG
Description
Non-Fucosylated Anti-Human MCSP (LC007) is a glycosylation-modified therapeutic biobetter antibody.
Antibody Indication
Melanoma
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced MCSP antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
CSPG4
Full Name
chondroitin sulfate proteoglycan 4
Background
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
Alternative Names
CSPG4; chondroitin sulfate proteoglycan 4; NG2; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG; chondroitin sulfate proteoglycan NG2; melanoma chondroitin sulfate proteoglycan; melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4 (melanoma-associated)
Gene ID
1464
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
LC007
Host
Humanized
Species Reactivity
Human
Description
The non-glycan engineered LC007 antibody (LC007wt) showed ADCC action, and the LC007 glycoengineered antibody (LC007g2) showed an increase in ADCC compared to non-glycan engineered LC007.
Antibody Indication
Melanoma

Related Products

Anti-MCSP Antibody, Non-Fucosylated (BioBet-749ZP) (CAT#: BioBet-749ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

  • *
  • *
  • *
USA

UK

Germany

ISO 9001 Certified - Creative Biolabs Quality Management System.