Target
Lysosomal-associated membrane protein family, member 5
Description
Anti-Lysosomal-associated membrane protein family Antibody, Non-Fucosylated (BioBet-1167ZP) is a humanized monoclonal IgG antibody against Lysosomal-associated membrane protein family, member 5. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Multiple Myeloma
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Lysosomal-associated membrane protein family, member 5 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Full Name
lysosomal-associated membrane protein family, member 5
Alternative Names
LAMP5; lysosomal-associated membrane protein family, member 5; LAMP-5; UNC-43; BADLAMP; BAD-LAMP; C20orf103; lysosome-associated membrane glycoprotein 5; LAMP family protein C20orf103; brain-associated LAMP-like protein; lysosome-associated membrane protein 5; brain and dendritic cell associated LAMP; brain and dendritic cell-associated LAMP
Cellular Localization
Plasma membrane, Endosome
Involvement in Disease
Diseases associated with LAMP5 include Epiphyseal Dysplasia, Multiple, 4 and Spinal Muscular Atrophy, Type Ii.
Function
Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain.
Post-translational modifications
1.Glycosylated 2.Modification sites at PhosphoSitePlus 3.Glycosylation at Asn35, Asn53, and Asn127
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Clone
BioBet-1167ZP
Description
This is a monoclonal antibody recognizing the extracellular region of LAMP5, demonstrated antibody-dependent cell-mediated cytotoxic activity, and cell growth inhibitory activity, against a multiple myeloma cell line.
Antibody Indication
Multiple Myeloma
