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Non-Fucosylated Anti-Human Lysosomal-associated membrane protein family (D2) Therapeutic Antibody (CAT#: BioBet-1168ZP) Datasheet

Target
Lysosomal-associated membrane protein family, member 5
Isotype
IgG
Description
ADCC-Enhanced anti-Lysosomal-associated membrane protein family, member 5 (D2) is a non-fucosylated therapeutic biobetter antibody engineered by Creative Biolabs' Afuco™ technology platform.
Antibody Indication
Multiple Myeloma
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Lysosomal-associated membrane protein family, member 5 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
LAMP5
Full Name
lysosomal-associated membrane protein family, member 5
Alternative Names
LAMP5; lysosomal-associated membrane protein family, member 5; LAMP-5; UNC-43; BADLAMP; BAD-LAMP; C20orf103; lysosome-associated membrane glycoprotein 5; LAMP family protein C20orf103; brain-associated LAMP-like protein; lysosome-associated membrane protein 5; brain and dendritic cell associated LAMP; brain and dendritic cell-associated LAMP
Gene ID
24141
Cellular Localization
Plasma membrane, Endosome
Involvement in Disease
Diseases associated with LAMP5 include Epiphyseal Dysplasia, Multiple, 4 and Spinal Muscular Atrophy, Type Ii.
Function
Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain.
Post-translational modifications
1.Glycosylated 2.Modification sites at PhosphoSitePlus 3.Glycosylation at Asn35, Asn53, and Asn127
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
D2
Host
Humanized
Species Reactivity
Human
Description
This is a monoclonal antibody recognizing the extracellular region of LAMP5, demonstrated antibody-dependent cell-mediated cytotoxic activity, and cell growth inhibitory activity, against a multiple myeloma cell line.
Antibody Indication
Multiple Myeloma

Multiple Myeloma

Related Products

Anti-Lysosomal-associated membrane protein family Antibody, Non-Fucosylated (CAT#: BioBet-1167ZP)
Non-Fucosylated Anti-Human Lysosomal-associated membrane protein family (D10) Therapeutic Antibody (CAT#: BioBet-1169ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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