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Anti-Human Ficolin-3 Monoclonal Antibody (clone 4H5) -10 mg (CAT#: CB-P500-K) Datasheet

Product Type
The monoclonal antibody 4H5 recognizes human Ficolin-3, also known as H-ficolin. Ficolins are a type of pattern recognition molecules that contain both collagen-like domains and fibrinogen-like domains, which can activate the complement system on the surface of microorganisms by binding to MASP. In humans, three types of Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin) and Ficolin-3 (H-ficolin). Ficolin-1 is mainly expressed by monocytes, granulocytes and lung cells, and is locally present in the inflammation area. Ficolin-3 (also known as Bodo Antigen, H-ficolin or Ficolin H) is produced by the liver and lungs. Ficolin-3 is associated with three types of MASP and sMAP, and the complex activates C4, C2 and C3 in the liquid phase.
100 µg

All products and services are for Research Use Only. Do Not use in humans.


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