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Creative Biolabs - ADCC+ Antibody

Anti-CD5 Antibody, Highly Galactosylated (BioBet-GA-155ZP) (CAT#: BioBet-GA-155ZP) Datasheet

Target
CD5
Isotype
IgG
Description
Anti-CD5 Antibody, Highly Galactosylated (BioBet-GA-155ZP) is a mouse IgG antibody against CD5 which contains with a high level of galactosylation.
Antibody Indication
Graft-versus-host disease (GvHD)
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD5 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
CD5
Full Name
CD5 Molecule
Background
CD5 (CD5 Molecule) is a Protein Coding gene.
Diseases associated with CD5 include Thymus Cancer and Richter's Syndrome.
Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and B Cell Development Pathways.
Gene Ontology (GO) annotations related to this gene include receptor activity and scavenger receptor activity.
Alternative Names
Zolimomab aritox;141483-72-9;H65-RTA;XomaZyme-H65;CD5;CD5 molecule;CD5 antigen (p56 62) , LEU1;T-cell surface glycoprotein CD5;T1;CD5 antigen (p56-62);lymphocyte antigen T1/Leu-1;LEU1;
Gene ID
921
UniProt ID
P06127
Cellular Localization
Plasma membrane
Genecards
1685
Involvement in Disease
Its related pathways are Hematopoietic cell lineage and Hematopoietic Stem Cells and Lineage-specific Markers.
Related Pathways
May act as a receptor in regulating T-cell proliferation.
Field of research
Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-GA-155ZP
Host
Mouse
Species Reactivity
Human
Description
Recombinant mouse monoclonal antibody scFv fragment expressed in E. Coli binding to human CD5. Zolimomab aritox is a mouse monoclonal antibody which has been investigated for the treatment of systemic lupus erythematosus and graft-versus-host disease, but the studies failed to show positive effects of the drug.It is an anti-CD5 antibody which is linked to the A chain of the ricin protein.
Antibody Indication
Graft-versus-host disease (GvHD)

Graft-versus-host disease (GvHD)

Related Products

Anti-CD5 Antibody, FcγRIIB Binding Enhanced (AES-0622-ZP584) (CAT#: AES-0622-ZP584)
Anti-CD5 Antibody, Recycling (AES-0622-ZP256) (CAT#: AES-0622-ZP256)
Anti-CD5 Antibody, Highly Galactosylated (BioBet-GA-156ZP) (CAT#: BioBet-GA-156ZP)
Anti-CD5 Antibody, Half-Life Extended (AES-0622-ZP1240) (CAT#: AES-0622-ZP1240)
Anti-CD5 Antibody, Non-Fucosylated (BioBet-155ZP) (CAT#: BioBet-155ZP)
Anti-CD5 Antibody, Non-Fucosylated (BioBet-156ZP) (CAT#: BioBet-156ZP)
Anti-CD5 Antibody, On-Target (AES-0622-ZP912) (CAT#: AES-0622-ZP912)

All products and services are for Research Use Only. Do Not use in humans.

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