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Creative Biolabs - ADCC+ Antibody

Anti-CD45 Antibody, ADCC Enchanced (BioBet-CB-060LX) (CAT#: BioBet-CB-060LX) Datasheet

Target
CD45
Isotype
IgG1
Description
Anti-CD45 Antibody, ADCC Enchanced (BioBet-CB-060LX) is a glycosylation-modified anti-CD45 therapeutic antibody.
Antibody Indication
Chronic lymphocytic leukemia; follicular lymphoma; some types of non-Hodgkin lymphoma (NHL);some non-cancer related illnesses
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD45 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
CD45
Full Name
Protein tyrosine phosphatase
Background
CD45 (lymphocyte common antigen) is a receptor-linked protein tyrosine phosphatase that is expressed on all leucocytes, and which plays a crucial role in the function of these cells.
Alternative Names
Protein tyrosine phosphatase; LSM; LPAP; LSM-1; CD-45
Gene ID
19265
UniProt ID
Q542J3
Field of research
Cell Biology, Immunology,
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1
Antibody Clone
BioBet-CB-060LX
Host
Murine
Species Reactivity
Human
Description
ADCC-Enhanced Anti-Human CD45 (apamistamab) Antibody is derived from clone apamistamab, which is a Murine monoclonal antibody with enhanced ADCC activity. Antibody-dependent cellular cytotoxicity (ADCC) is an important function of antibody. It is a part of the humoral immune response to limit and contain infection. The antibody targets the CD45, and it is intended for the research of AML.
Antibody Indication
AML

AML

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All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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