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Anti-CD252 Antibody, Highly Galactosylated (BioBet-GA-481ZP) (CAT#: BioBet-GA-481ZP) Datasheet

Target
CD252
Isotype
IgG4, κ
Description
Anti-CD252 Antibody, Highly Galactosylated (BioBet-GA-481ZP) is a human IgG4, κ antibody against CD252 which contains with a high level of galactosylation.
Antibody Indication
Asthma
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD252 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TNFSF4
Full Name
TNFSF4 Gene(Protein Coding)


TNF Superfamily Member 4
Background
This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Alternative Names
Oxelumab;1186098-83-8;RO4989991;RG4930;huMAb OX40L;TNFSF4;tumor necrosis factor (ligand) superfamily, member 4;tax transcriptionally activated glycoprotein 1, 34kD , TXGP1;tumor necrosis factor ligand superfamily member 4;CD252;gp34;OX 40L;OX40L;CD134 lig
Gene ID
7292
UniProt ID
P23510
Cellular Localization
Membrane
Genecards
11934
Involvement in Disease
Its related pathways are PEDF Induced Signaling and TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions.
Related Pathways
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
Field of research
1.Glycosylation at Asn90, Asn114, Asn152, and Asn157 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG4, κ
Antibody Clone
BioBet-GA-481ZP
Host
Human
Species Reactivity
Human
Description
The Highly Galactosylated Anti-CD252 (Oxelumab), a biobetter antibody contains with a high level of galactosylation.
Antibody Indication
Asthma

Asthma

Related Products

Anti-CD252 Antibody, Recycling (AES-0622-ZP328) (CAT#: AES-0622-ZP328)
Anti-CD252 Antibody, FcγRIIB Binding Enhanced (AES-0622-ZP656) (CAT#: AES-0622-ZP656)
Anti-CD252 Antibody, On-Target (AES-0622-ZP984) (CAT#: AES-0622-ZP984)
Anti-CD252 Antibody, Non-Fucosylated (BioBet-481ZP) (CAT#: BioBet-481ZP)
Anti-CD252 Antibody, Half-Life Extended (AES-0622-ZP1312) (CAT#: AES-0622-ZP1312)

All products and services are for Research Use Only. Do Not use in humans.

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Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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