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Anti-CD15/FUT4 Antibody, Highly Galactosylated (BioBet-GA-240ZP) (CAT#: BioBet-GA-240ZP) Datasheet

Target
CD15/FUT4
Isotype
IgG
Description
Anti-CD15/FUT4 Antibody, Highly Galactosylated (BioBet-GA-240ZP) is a mouse IgG antibody against CD15/FUT4 which contains with a high level of galactosylation.
Antibody Indication
Appendicitis (Radionuclide imaging)
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD15/FUT4 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
FUT4
Full Name
Fucosyltransferase 4
Background
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009]
Alternative Names
technetium (99mTc) fanolesomab;neutrospec;225239-31-6;FUT4;fucosyltransferase 4 (alpha (1, 3) fucosyltransferase, myeloid-specific);CD15, ELFT, FCT3A;alpha-(1, 3)-fucosyltransferase;ELAM ligand fucosyltransferase;FUC TIV;galactoside 3 L fucosyltransferase
Gene ID
UniProt ID
Cellular Localization
Golgi apparatus
Genecards
Involvement in Disease
Its related pathways are Glycosphingolipid biosynthesis - lacto and neolacto series and Metabolism.
Related Pathways
May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Field of research
1.Glycosylation at Asn216 and Asn315 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-GA-240ZP
Host
Mouse
Species Reactivity
Human
Description
Recombinant mouse monoclonal antibody expressed in CHO binding to human CD15/FUT4. Technetium (99mTc) fanolesomab is a mouse monoclonal antibody formerly used to aid in the diagnosis of appendicitis. It is labeled with a radioisotope, technetium-99m (99mTc).
Antibody Indication
Appendicitis (Radionuclide imaging)

Appendicitis (Radionuclide imaging)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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