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Non-fucosylated Anti-Human TAG72 (Satumomab) Therapeutic Antibody (CAT#: BioBet-449ZP) Datasheet

Target
TAG72
Isotype
IgG1, κ
Description
ADCC-enhanced Satumomab is a non-fucosylated anti-TAG72 therapeutic biobetter antibody.
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced TAG72 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TAG72
Alternative Names
Minretumomab; 195189-17-4; CA 72.4; TAG 72; Tumor associated Glycoprotein 72
Cellular Localization
Nucleus
Involvement in Disease
Diseases associated with RNMT include Bowen-Conradi Syndrome and Microphthalmia, Isolated 6.
Related Pathways
Its related pathways are HIV Transcription Elongation and Gene Expression.
Function
The catalytic subunit of mrna-cap methyltransferase RNMT:RAMAC complex, which methylates the N7 position of the added guanosine to the 5'cap structure of mRNAs. Binding RNA containing 5'end GpppC.
Post-translational modifications
1.Ubiquitination at Lys163 and Lys208 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1, κ
Antibody Clone
Satumomab
Host
Mouse
Species Reactivity
Human
Description
ADCC-enhanced Satumomab is a non-fucosylated anti-TAG72 therapeutic biobetter antibody.

Related Products

Highly Galactosylated Anti-TAG72 (Satumomab Pendetide) Antibody (CAT#: BioBet-GA-450ZP)
Non-fucosylated Anti-Human TAG72 (Satumomab Pendetide) Therapeutic Antibody (CAT#: BioBet-450ZP)
Non-fucosylated Anti-Human TAG72 (Minretumomab) Therapeutic Antibody (CAT#: BioBet-448ZP)
Highly Galactosylated Anti-TAG72 (Minretumomab) Antibody (CAT#: BioBet-GA-448ZP)
Highly Galactosylated Anti-TAG72 (Satumomab) Antibody (CAT#: BioBet-GA-449ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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