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Anti-Seizure protein 6 homolog Antibody, Non-Fucosylated (CAT#: BioBet-1281ZP) Datasheet

Target
Seizure protein 6 homolog
Isotype
IgG
Description
Anti-Seizure protein 6 homolog Antibody, Non-Fucosylated (BioBet-1281ZP) is a humanized monoclonal IgG antibody against Seizure protein 6 homolog. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Seizure protein 6 homolog antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
SEZ6
Full Name
seizure related 6 homolog (mouse)
Background
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Names
SEZ6; seizure related 6 homolog (mouse); seizure protein 6 homolog; SEZ-6; hSEZ-6
Gene ID
124925
Cellular Localization
Plasma membrane
Involvement in Disease
Diseases associated with SEZ6 include Febrile Seizures and Dystonia 12.
Function
May play a role in cell-cell recognition and neuronal membrane signaling. It seems to be important to achieve the necessary balance between dendrite elongation and branching in refining a complex dendritic arbor. Participate in the development of appropriate excitatory synaptic connections (through similarity).
Post-translational modifications
O-glycosylated.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-1281ZP
Host
Humanized
Species Reactivity
Human
Description
The anti-SEZ6 antibody are useful for various diseases or disorders including proliferative disorders such as cancer.
Antibody Indication
Cancer

Cancer

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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