Book a Meeting

Non-Fucosylated Anti-Human Ovr115 (Ovr115.F76.2) Therapeutic Antibody (CAT#: BioBet-1370ZP) Datasheet

Target
Ovr115
Isotype
IgG
Description
ADCC-Enhanced anti-Ovr115 (Ovr115.F76.2) is a non-fucosylated therapeutic biobetter antibody engineered by Creative Biolabs' Afuco™ technology platform.
Indication
Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Ovr115 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TMPRSS4
Full Name
transmembrane protease, serine 4
Background
This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Names
TMPRSS4; transmembrane protease, serine 4; CAPH2; MT-SP2; TMPRSS3; transmembrane protease serine 4; channel-activating protease 2; membrane-type serine protease 2; transmembrane serine protease 3; type II membrane serine protease
Gene ID
56649
Cellular Localization
Membrane
Involvement in Disease
Diseases associated with TMPRSS4 include Autosomal Recessive Cerebral Atrophy and Deafness, Autosomal Recessive 8.
Related Pathways
Its related pathways are Measles.
Function
Probable protease. Seems to be capable of activating ENaC (By similarity).
Field of research
Cancer antibody; Cell Biology and Cellular Response antibody; Neuroscience antibody
Post-translational modifications
1.Glycosylation at Asn130 and Asn178 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
Ovr115.F76.2
Host
Humanized
Species Reactivity
Human
Description
The anti-ovarian antibody that bind to Ovr115 are used in treating pancreatic, lung or breast cancer.
Indication
Cancer

Cancer

Related Products

Non-Fucosylated Anti-Human Ovr115 (Ovr115.D84.2) Therapeutic Antibody (CAT#: BioBet-1371ZP)
Non-Fucosylated Anti-Human Ovr115 (Ovr115.F21.1) Therapeutic Antibody (CAT#: BioBet-1372ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

  • *
  • *
  • *
USA

UK

Germany

ISO 9001 Certified - Creative Biolabs Quality Management System.