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Non-Fucosylated Anti-Human EphA3 (antibody 1) Therapeutic Antibody (CAT#: BioBet-1680ZP) Datasheet

Target
EphA3
Isotype
IgG
Description
Non-Fucosylated Anti-Human EphA3 (antibody 1) is a glycosylation-modified therapeutic biobetter antibody.
Antibody Indication
Myelodysplastic syndrome, Myelofibrosis, Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced EphA3 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
EPHA3
Full Name
EPH Receptor A3
Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
Alternative Names
Ephrin receptor A3; EPH receptor A3; ephrin type-A receptor 3; tyrosine protein kinase TYR04; tyrosine-protein kinase receptor REK4; ETK; ETK1; HEK; HEK4
Gene ID
2042
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
antibody 1
Host
Humanized
Species Reactivity
Human
Description
Non-fucosylated antibody 1 shows increased ADCC activity against EphA3-positive target cells compared to fucosylated antibody 1.
Antibody Indication
Myelodysplastic syndrome, Myelofibrosis, Cancer

Related Products

Anti-EPHA3 Antibody, FcγRIIB Binding Enhanced (CAT#: AES-0622-ZP454)
Anti-EPHA3 Antibody, Half-Life Extended (CAT#: AES-0622-ZP1110)
Anti-EPHA3 Antibody, Highly Galactosylated (CAT#: BioBet-GA-217ZP)
Anti-EPHA3 Antibody, On-Target (CAT#: AES-0622-ZP782)
Anti-EPHA3 Antibody, Recycling (CAT#: AES-0622-ZP126)
Anti-EPHA3 Antibody, Non-Fucosylated (CAT#: BioBet-217ZP)

All products and services are for Research Use Only. Do Not use in humans.

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