Description
Non-Fucosylated Anti-Human CD19 (4G7) is a glycosylation-modified therapeutic biobetter antibody.
Antibody Indication
Refractory B cell precursor Acute lymphoblastic leukemia
Relapsed B cell precursor Acute lymphoblastic leukemia
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD19 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Description
MAb 4G7 is produced by using the human mammalian 293T cell line in the presence of the beta (1,4) -N-acetylglucosaminyltransferase III (GnTIII) enzyme, (1) at least 60% N-acetylglucosamine. Produced under conditions effective to produce Fc fragments in antibodies characterized by bisecting oligosaccharides and (2) Asn297-linked oligosaccharides containing only 10% non-fucosylated N-acetylglucosamine bisecting oligosaccharides It was.
Antibody Indication
Refractory B cell precursor Acute lymphoblastic leukemia
Relapsed B cell precursor Acute lymphoblastic leukemia
