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Highly Galactosylated Anti-PVRL4 (Enfortumab) Antibody (CAT#: BioBet-GA-418ZP) Datasheet

Target
PVRL4
Isotype
IgG1, κ
Description
The Highly Galactosylated Anti-PVRL4 (Enfortumab), a biobetter antibody contains with a high level of galactosylation.
Indication
Solid tumors
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced PVRL4 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
PVRL4
Alternative Names
PVRL4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; LNIR; nectin 4; PRR4; Ig superfamily receptor LNIR; Nectin 4; Nectin-4; poliovirus receptor-related 4
UniProt ID
Q96NY8
Cellular Localization
Extracellular region or secreted, Plasma membrane
Genecards
19688
Involvement in Disease
Its related pathways are Cell junction organization and Adhesion.
Related Pathways
It appears to be involved in cell adhesion through trans-homotype and -heterotype interactions, the latter including specific interactions with NECTIN1. It cannot be used as a receptor for herpes viruses to enter cells.
Field of research
The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1, κ
Antibody Clone
Enfortumab
Host
Human
Species Reactivity
Human
Description
The Highly Galactosylated Anti-PVRL4 (Enfortumab), a biobetter antibody contains with a high level of galactosylation.
Indication
Solid tumors

Solid tumors

Related Products

Non-fucosylated Anti-Human PVRL4 (Enfortumab) Therapeutic Antibody (CAT#: BioBet-418ZP)
Highly Galactosylated Anti-PVRL4 (enfortumab vedotin) Antibody (CAT#: BioBet-GA-419ZP)
BetterBet™ Anti-PVRL4 FcγRIIB Binding Enhanced Antibody (CAT#: AES-0622-ZP436)
BetterBet™ Anti-PVRL4 Recycling Antibody (CAT#: AES-0622-ZP108)
Non-fucosylated Anti-Human PVRL4 (enfortumab vedotin) Therapeutic Antibody (CAT#: BioBet-419ZP)
BetterBet™ Anti-PVRL4 Half-Life Extended Antibody (CAT#: AES-0622-ZP1092)
BetterBet™ Anti-PVRL4 On-Target Antibody (CAT#: AES-0622-ZP764)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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