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Highly Galactosylated Anti-IFN alpha (Rontalizumab) Antibody (CAT#: BioBet-GA-263ZP) Datasheet

Target
IFN alpha
Isotype
IgG1, κ
Description
The Highly Galactosylated Anti-IFN alpha (Rontalizumab), a biobetter antibody contains with a high level of galactosylation.
Indication
Systemic lupus erythematosus (SLE)
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced IFN alpha antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
IFNA1
Full Name
Interferon Alpha 1
Background
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011]
Alternative Names
Rontalizumab;948570-30-7;rhuMAb IFN alpha;RG7415;IFNA1;interferon, alpha 1;interferon alpha-1/13;IFL;IFN;IFN ALPHA;IFN alpha 1b;IFN alphaD;IFNA13;IFNA@;interferon alpha 1b;leIF D;IFN-alpha 1b;IFN-alpha-1/13;interferon-alpha1;interferon alpha-D;IFN-ALPHA;I
Gene ID
3439
UniProt ID
P01562
Cellular Localization
Extracellular region or secreted
Genecards
5417
Involvement in Disease
Its related pathways are all-trans-Retinoic Acid Mediated Apoptosis and Tuberculosis.
Related Pathways
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Field of research
1.Modification sites at PhosphoSitePlus 2.Modification sites at neXtProt
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1, κ
Antibody Clone
Rontalizumab
Host
Humanized
Species Reactivity
Human
Description
Recombinant monoclonal antibody to IFN alpha. Rontalizumab is a humanized monoclonal antibody. for treatment of systemic lupus erythematosus.
Indication
Systemic lupus erythematosus (SLE)

Systemic lupus erythematosus (SLE)

Related Products

BetterBet™ Anti-IFN alpha On-Target Antibody (CAT#: AES-0622-ZP956)
BetterBet™ Anti-IFN alpha Half-Life Extended Antibody (CAT#: AES-0622-ZP1284)
Non-fucosylated Anti-Human IFN alpha (Rontalizumab) Therapeutic Antibody (CAT#: BioBet-263ZP)
BetterBet™ Anti-IFN alpha Recycling Antibody (CAT#: AES-0622-ZP300)
BetterBet™ Anti-IFN alpha FcγRIIB Binding Enhanced Antibody (CAT#: AES-0622-ZP628)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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