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Highly Galactosylated Anti-CD15/FUT4 (technetium (99mTc) fanolesomab) Antibody (CAT#: BioBet-GA-240ZP) Datasheet

Target
CD15/FUT4
Isotype
IgG
Description
The Highly Galactosylated Anti-CD15/FUT4 (technetium (99mTc) fanolesomab), a biobetter antibody contains with a high level of galactosylation.
Indication
Appendicitis (Radionuclide imaging)
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced CD15/FUT4 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
FUT4
Full Name
Fucosyltransferase 4
Background
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009]
Alternative Names
technetium (99mTc) fanolesomab;neutrospec;225239-31-6;FUT4;fucosyltransferase 4 (alpha (1, 3) fucosyltransferase, myeloid-specific);CD15, ELFT, FCT3A;alpha-(1, 3)-fucosyltransferase;ELAM ligand fucosyltransferase;FUC TIV;galactoside 3 L fucosyltransferase
Gene ID
2526
UniProt ID
P22083
Cellular Localization
Golgi apparatus
Genecards
4015
Involvement in Disease
Its related pathways are Glycosphingolipid biosynthesis - lacto and neolacto series and Metabolism.
Related Pathways
May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Field of research
1.Glycosylation at Asn216 and Asn315 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
technetium (99mTc) fanolesomab
Host
Mouse
Species Reactivity
Human
Description
Recombinant mouse monoclonal antibody expressed in CHO binding to human CD15/FUT4. Technetium (99mTc) fanolesomab is a mouse monoclonal antibody formerly used to aid in the diagnosis of appendicitis. It is labeled with a radioisotope, technetium-99m (99mTc).
Indication
Appendicitis (Radionuclide imaging)

Appendicitis (Radionuclide imaging)

Related Products

BetterBet™ Anti-CD15/FUT4 On-Target Antibody (CAT#: AES-0622-ZP949)
BetterBet™ Anti-CD15/FUT4 Half-Life Extended Antibody (CAT#: AES-0622-ZP1277)
BetterBet™ Anti-CD15/FUT4 FcγRIIB Binding Enhanced Antibody (CAT#: AES-0622-ZP621)
BetterBet™ Anti-CD15/FUT4 Recycling Antibody (CAT#: AES-0622-ZP293)
Non-fucosylated Anti-Human CD15/FUT4 (technetium (99mTc) fanolesomab) Therapeutic Antibody (CAT#: BioBet-240ZP)

All products and services are for Research Use Only. Do Not use in humans.

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Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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