Description
Fc Engineered Anti-Human TNFRSF10A Antibody, CDC-Enhanced (Biobet-C465ZP) is a recombinant monoclonal Human IgG1 antibody against TNFRSF10A. This product is a CDC enhanced antibody produced by our proprietary platform.
Indication
Colorectal cancers
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced rituximab. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TNFRSF10A
Full Name
TNFRSF10A Gene(Protein Coding)
TNF Receptor Superfamily Member 10a
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Gene ID
8797
UniProt ID
O00220
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
Human IgG1
Indication
Colorectal cancers
