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Fc Engineered Anti-Human TNF Antibody, CDC-Enhanced (CAT#: BioBet-C021ZP) Datasheet

Target
TNF
Isotype
Whole Chimeric Antibody
Description
Fc Engineered Anti-Human TNF Antibody, CDC-Enhanced (BioBet-C021ZP) is a recombinant monoclonal Whole Chimeric antibody against TNF. This product is a CDC enhanced antibody produced by our proprietary platform.
Indication
Ankylosing Spondylitis (AS)
Crohn's Disease (CD)
Psoriasis Vulgaris (Plaque Psoriasis)
Psoriatic Arthritis
Rheumatoid Arthritis
Ulcerative Colitis
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Infliximab. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TNF
Full Name
tumor necrosis factor
Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Gene ID
7124
UniProt ID
P01375
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
Chimeric IgG1
Indication
Ankylosing Spondylitis (AS)
Crohn's Disease (CD)
Psoriasis Vulgaris (Plaque Psoriasis)
Psoriatic Arthritis
Rheumatoid Arthritis
Ulcerative Colitis

Ankylosing Spondylitis (AS)
Crohn's Disease (CD)
Psoriasis Vulgaris (Plaque Psoriasis)
Psoriatic Arthritis
Rheumatoid Arthritis
Ulcerative Colitis

Related Products

Fc Engineered Anti-Human TNF Therapeutic Antibody, a CDC-Enhanced Biobetter [Lot: CB20-PZ462] (CAT#: Biobet-C462ZP)
Fc Engineered Anti-Human TNF Therapeutic Antibody, a CDC-Enhanced Biobetter [Lot: CB20-PZ461] (CAT#: Biobet-C461ZP)
Fc Engineered Anti-Human TNF Therapeutic Antibody, a CDC-Enhanced Biobetter [Lot: CB20-PZ458] (CAT#: Biobet-C458ZP)
Fc Engineered Anti-Human TNF Therapeutic Antibody, a CDC-Enhanced Biobetter [Lot: CB20-PZ26] (CAT#: BioBet-C026ZP)
Fc Engineered Anti-Human TNF Therapeutic Antibody, a CDC-Enhanced Biobetter [Lot: CB20-PZ460] (CAT#: Biobet-C460ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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