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BetterBet™ Anti-TNFα Recycling Antibody (CAT#: AES-0622-ZP261) Datasheet

Target
TNFα
Description
This is a anti-TNFα recycling antibody provided by Creative Biolabs.
Applications
Enhanced mouse antigen eliminating
Technology
Antibody variable/constant engineering

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced TNFα antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TNFA
Full Name
TNF alpha
Alternative Names
Tumor Necrosis Factor; Tumor Necrosis Factor Ligand Superfamily Member 2; Cachectin; TNF-Alpha; TNFSF2; TNF-A; TNFA; Tumor Necrosis Factor (TNF Superfamily; Member 2); Tumor Necrosis Factor Ligand 1F
Description
This is a anti-TNFα recycling antibody provided by Creative Biolabs.

A recycling antibody combines two antibody engineering techniques: one is variable region engineering, which enables the antibody to bind to the antigen in the plasma and dissociate from the antigen in the endosome (after which the antigen undergoes lysosomal degradation), the other is constant region engineering to increase cellular uptake of antibody-antigen complexes into endosomes.

Related Products

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BetterBet™ Anti-TNFα On-Target Antibody (CAT#: AES-0622-ZP917)
BetterBet™ Anti-TNFα FcγRIIB Binding Enhanced Antibody (CAT#: AES-0622-ZP589)
Non-fucosylated Anti-Human TNFα (Ustekinumab) Therapeutic Antibody (CAT#: BioBet-032ZP)
Highly Galactosylated Anti-TNFα (Afelimomab) Antibody (CAT#: BioBet-GA-464ZP)
Non-fucosylated Anti-Human TNFα (Afelimomab) Therapeutic Antibody (CAT#: BioBet-464ZP)
BetterBet™ Anti-TNFα Half-Life Extended Antibody (CAT#: AES-0622-ZP1245)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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