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Anti-TIP-1 Antibody, Non-Fucosylated (BioBet-1661ZP) (CAT#: BioBet-1661ZP) Datasheet

Target
TIP-1
Isotype
IgG
Description
Anti-TIP-1 Antibody, Non-Fucosylated (BioBet-1661ZP) is a human monoclonal IgG antibody against TIP-1. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Tumor
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced TIP-1 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TIP-1
Full Name
TIP-1
Background
TIP-1 is specially expressed on tumor cells.
Alternative Names
TIP-1
Cellular Localization
Plasma membrane, Nucleus
Involvement in Disease
Diseases associated with TAX1BP3 include Cystinosis and Cystinosis, Nephropathic.
Related Pathways
Its related pathways are Signaling by GPCR and RHO GTPases Activate Rhotekin and Rhophilins.
Function
It is possible to regulate many protein-protein interactions by competing for PDZ domain binding sites. Binding to CTNNB1, which may become an inhibitor of Wnt signaling pathway. Competing with LIN7A for the combination of KCNJ4, thereby promoting the internalization of KCNJ4. May play a role in the Rho signaling pathway. It may be involved in the activation of CDC42 by the viral protein HPV16 E6.
Post-translational modifications
1.Ubiquitination at Lys116 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-1661ZP
Host
Human
Species Reactivity
Humanized
Description
The isolated antibody bind to TIP-1. And the antibody are useful in the recognition of tumor cells and tumor specific delivery of drugs and therapies.
Antibody Indication
Tumor

Tumor

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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