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Creative Biolabs - ADCC+ Antibody

Anti-Teneurin M4 Antibody, Non-Fucosylated (BioBet-1330ZP) (CAT#: BioBet-1330ZP) Datasheet

Target
Teneurin M4
Isotype
IgG
Description
ADCC-Enhanced anti-Teneurin M4 (1.44) is a non-fucosylated therapeutic biobetter antibody engineered by Creative Biolabs' Afuco™ technology platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Teneurin M4 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
TENM4
Full Name
teneurin transmembrane protein 4
Alternative Names
TENM4; teneurin transmembrane protein 4; Doc4; ODZ4; TNM4; Ten-M4; odd Oz/ten-m homolog 4; odz, odd Oz/ten-m homolog 4; protein Odd Oz/ten-m homolog 4; ten-4; tenascin-M4
Gene ID
26011
Cellular Localization
Plasma membrane, Nucleus
Involvement in Disease
Diseases associated with TENM4 include Tremor, Hereditary Essential, 5 and Tremor.
Function
Participate in neurodevelopment and regulate the establishment of proper connections in the nervous system. Play a role in the establishment of the anterior and posterior axis of the gastrulation Regulates the differentiation of oligodendrocytes and the formation of cellular processes in the central nervous system, as well as the myelination of small diameter axons. Promote the activation of focal adhesion kinase. Can be used as a cellular signal converter (through similarity).
Post-translational modifications
1.Glycosylation at Asn467, Asn940, Asn1259, Asn1609, Asn1705, Asn1741, Asn1799, Asn1884, Asn1985, Asn2188, Asn2328, and Asn26462.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
1.44
Host
Human
Species Reactivity
Human
Description
The fully human antibody directed to Ten-M4 can be used for delivering an agent, such as a toxin, to a particular target.
Antibody Indication
Cancer

Cancer

Related Products

Anti-Teneurin M4 Antibody, Non-Fucosylated (BioBet-1329ZP) (CAT#: BioBet-1329ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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