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Creative Biolabs - ADCC+ Antibody

Anti-Synaptophysin Antibody, Non-Fucosylated (C1-3) (CAT#: BioBet-1317ZP) Datasheet

Target
Synaptophysin
Isotype
scAb
Description
Anti-Synaptophysin Antibody, Non-Fucosylated (BioBet-1317ZP) is a human monoclonal scAb antibody against Synaptophysin. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Neuroendocrine Tumor
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Synaptophysin antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
SYP
Full Name
synaptophysin
Background
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).
Alternative Names
SYP; synaptophysin; MRX96; MRXSYP; major synaptic vesicle protein P38
Gene ID
6855
Cellular Localization
synaptic vesicle membrane, Multi-pass membrane protein, synaptosome
Involvement in Disease
Diseases associated with SYP include Mental Retardation, X-Linked 96 and Non-Syndromic X-Linked Intellectual Disability.
Related Pathways
Its related pathways are Neuroscience and Neural Stem Cells and Lineage-specific Markers.
Function
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Post-translational modifications
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
scAb
Antibody Clone
C1-3
Host
Human
Species Reactivity
Human
Description
The monoclonal antibody againsts synaptophysin is useful to locate a primary focus of the neuroendocrine tumor.
Antibody Indication
Neuroendocrine Tumor

Neuroendocrine Tumor

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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