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Anti-sPLA2-X Antibody, Non-Fucosylated (CAT#: BioBet-1536ZP) Datasheet

Target
sPLA2-X
Isotype
IgG
Description
Anti-sPLA2-X Antibody, Non-Fucosylated (BioBet-1536ZP) is a human monoclonal IgG antibody against sPLA2-X. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cardiovascular Disease
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced sPLA2-X antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
PLA2G10
Full Name
phospholipase A2, group X
Alternative Names
PLA2G10; phospholipase A2, group X; SPLA2; GXPLA2; GXSPLA2; group 10 secretory phospholipase A2; sPLA2-X; GX sPLA2; group X secretory phospholipase A2; phosphatidylcholine 2-acylhydrolase 10;
Gene ID
8399
Cellular Localization
Extracellular region or secreted, Lysosome
Involvement in Disease
Diseases associated with PLA2G10 include Acute Chest Syndrome and Meconium Aspiration Syndrome.
Related Pathways
Its related pathways are Sweet Taste Signaling and Acyl chain remodelling of PE
Function
PA2 catalyzes the calcium-dependent hydrolysis of 2-acyl groups in 3-sn-phosphoglycerolipids. It has the powerful effect of releasing arachidonic acid from cell membrane phospholipids. Phosphatidylethanolamine and phosphatidylcholine liposomes are superior to phosphatidylserine liposomes.
Post-translational modifications
Glycosylation at Asn113
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
9C12
Host
Human
Species Reactivity
Human
Description
The novel antibody against human group X secreted phospholipase A2 (sPLA2-X) can be used for the treatment of cardiovascular disease.
Antibody Indication
Cardiovascular Disease

Cardiovascular Disease

Related Products

Non-Fucosylated Anti-Human sPLA2-X (8D9) Therapeutic Antibody (CAT#: BioBet-1537ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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