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Anti-Semaphorin 4B Antibody, Non-Fucosylated (BioBet-1274ZP) (CAT#: BioBet-1274ZP) Datasheet

Target
Semaphorin 4B
Isotype
IgG
Description
Anti-Semaphorin 4B Antibody, Non-Fucosylated (BioBet-1274ZP) is a humanized monoclonal IgG antibody against Semaphorin 4B. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Semaphorin 4B antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
SEMA4B
Full Name
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Alternative Names
SEMA4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; SemC; SEMAC; semaphorin-4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4B
Gene ID
10509
Cellular Localization
Membrane
Involvement in Disease
Diseases associated with SEMA4B include Epilepsy, Familial Temporal Lobe, 8 and Kabuki Syndrome 1.
Related Pathways
Its related pathways are Neuroscience and NF-KappaB Family Pathway.
Function
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Post-translational modifications
1.Glycosylation at Asn69, Asn96, Asn165, Asn410, Asn525, and Asn630 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-1274ZP
Host
Humanized
Species Reactivity
Human
Description
The anti-sema4B antibody are useful in preventing and treating cancer.
Antibody Indication
Cancer

Cancer

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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