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Creative Biolabs - ADCC+ Antibody

Anti-Respiratory Syncytial Virus Antibody, Non-Fucosylated (Sym003) (CAT#: BioBet-1245ZP) Datasheet

Target
Respiratory Syncytial Virus
Isotype
IgG
Description
Anti-Respiratory Syncytial Virus Antibody, Non-Fucosylated (BioBet-1245ZP) is a human monoclonal IgG antibody against Respiratory Syncytial Virus. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Respiratory syncytial virus infection
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Respiratory Syncytial Virus antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
RSV
Full Name
Respiratory Syncytial Virus
Background
Human respiratory syncytial virus (RSV) is a virus that causes respiratory tract infections. It is a major cause of lower respiratory tract infections and hospital visits during infancy and childhood.
Alternative Names
RSV; Respiratory Syncytial Virus; Human respiratory syncytial virus
Cellular Localization
Plasma membrane
Involvement in Disease
Diseases associated with CTLA4 include Autoimmune Lymphoproliferative Syndrome, Type V and Celiac Disease 3.
Related Pathways
Its related pathways are TCR Signaling (Qiagen) and T cell receptor signaling pathway.
Function
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Post-translational modifications
1.N-glycosylation is important for dimerization. 2.Phosphorylation at Tyr-201 prevents binding to the AP-2 adapter complex, blocks endocytosis, and leads to retention of CTLA4 on the cell surface.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
Sym003
Host
Human
Species Reactivity
RSV
Description
Sym003 is a recombinant polyclonal antibody that contains antibody binding to non-overlapping epitopes on the two major antigens on respiratory syncytial virus for the treatment of respiratory infections.
Antibody Indication
Respiratory syncytial virus infection

Respiratory syncytial virus infection

Related Products

Anti-Respiratory Syncytial Virus Antibody, Non-Fucosylated (BioBet-427ZP) (CAT#: BioBet-427ZP)
Anti-respiratory syncytial virus Antibody, Highly Galactosylated (BioBet-GA-427ZP) (CAT#: BioBet-GA-427ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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