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Anti-Prokineticin receptor 1 Antibody, Non-Fucosylated (H4H6385N) (CAT#: BioBet-1549ZP) Datasheet

Target
Prokineticin receptor 1
Isotype
IgG
Description
Anti-Prokineticin receptor 1 Antibody, Non-Fucosylated (BioBet-1549ZP) is a mouse monoclonal IgG antibody against Prokineticin receptor 1. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Pain Conditions; Pathological Angiogenesis Condions
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Prokineticin receptor 1 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
PROKR1
Full Name
prokineticin receptor 1
Alternative Names
PROKR1; prokineticin receptor 1; ZAQ; PKR1; GPR73; GPR73a; PK-R1; G protein-coupled receptor 73; G-protein coupled receptor 73; G protein-coupled receptor ZAQ; G-protein coupled receptor ZAQ;
Gene ID
10887
Cellular Localization
Plasma membrane
Involvement in Disease
Diseases associated with PROKR1 include Ectopic Pregnancy and Kallmann Syndrome.
Related Pathways
Its related pathways are RET signaling and Signaling by GPCR.
Function
Prokineticin 1 receptor. Only binds to the G(q) subclass of isoform G protein. Activation leads to the mobilization of calcium, stimulates phosphoinositide metabolism and activates p44/p42 mitogen-activated protein kinase. May play a role in early pregnancy
Post-translational modifications
1.Glycosylation at Asn11, Asn14, and Asn36 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
H4H6385N
Host
Mouse
Species Reactivity
Human
Description
The antibody that bind to cell surface-expressed prokineticin receptors (PROKRs), and the antibody are useful for the treatment of various diseases and disorders mediated by prokineticin signaling, such as pain conditions and pathological angiogenesis condions.
Antibody Indication
Pain Conditions; Pathological Angiogenesis Condions

Pain Conditions; Pathological Angiogenesis Condions

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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