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Anti-PGF Antibody, Non-Fucosylated (CAT#: BioBet-1500ZP) Datasheet

Target
PGF
Isotype
IgG2
Description
Anti-PGF Antibody, Non-Fucosylated (BioBet-1500ZP) is a Rat monoclonal IgG2 antibody against PGF. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Colon Carcinomas; Mmammary Carcinomas
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced PGF antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
PGF
Full Name
PGF; placental growth factor; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760; placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein;
Background
This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]
Alternative Names
placental growth factor
Gene ID
5228
Cellular Localization
Extracellular region or secreted
Involvement in Disease
Diseases associated with PGF include Placental Insufficiency and Twin-To-Twin Transfusion Syndrome.
Related Pathways
Its related pathways are Signaling by GPCR and NF-KappaB Family Pathway.
Function
Growth factors play a role in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. The heterotypic PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. It also promotes the growth of cell tumors.
Field of research
Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody
Post-translational modifications
N-glycosylated.
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG2
Antibody Clone
BioBet-1500ZP
Host
Rat
Species Reactivity
Human
Description
Anti-PLGF antibody recgonizes Placental Growth Factor (PLGF), and is used for the treatment of colon and mammary carcinomas.
Antibody Indication
Colon Carcinomas; Mmammary Carcinomas

Colon Carcinomas; Mmammary Carcinomas

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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