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Anti-PERP Antibody, Non-Fucosylated (BioBet-1572ZP) (CAT#: BioBet-1572ZP) Datasheet

Target
p53 apoptosis effector related to PMP-22
Isotype
IgG
Description
Anti-PERP Antibody, Non-Fucosylated (BioBet-1572ZP) is a Rabbit monoclonal IgG antibody against p53 apoptosis effector related to PMP-22. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced p53 apoptosis effector related to PMP-22 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
PERP
Full Name
PERP, TP53 apoptosis effector
Alternative Names
PERP; PERP, TP53 apoptosis effector; THW; KCP1; PIGPC1; KRTCAP1; dJ496H19.1; p53 apoptosis effector related to PMP-22; KCP-1; 1110017A08Rik; transmembrane protein THW; p53-induced protein PIGPC1; keratinocyte associated protein 1; keratinocyte-associated protein 1; keratinocytes associated protein 1; p53 apoptosis effector related to PMP22;
Gene ID
Cellular Localization
Plasma membrane
Involvement in Disease
Diseases associated with PERP include Palmoplantar Keratoderma, Mutilating, With Periorificial Keratotic Plaques and Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate.
Related Pathways
Its related pathways are Keratinization and TP53 Regulates Transcription of Cell Death Genes.
Function
Part of the desmosome connection between cells. By promoting desmosome assembly, it plays a role in stratified epithelial integrity and cell-cell adhesion. Acts in the tp53-dependent apoptotic pathway (similarity).
Field of research
Cell Biology and Cellular Response antibody; Cell Death antibody; Signaling Transduction antibody
Post-translational modifications
No Post-translational modifications
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-1572ZP
Host
Rabbit
Species Reactivity
Human
Description
The anti-PERP antibody recognized residues at the C terminus of Human PERP. It can be used for cancer treatment.
Antibody Indication
Cancer

Cancer

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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