Book a Meeting

Anti-PAD2 Antibody, Non-Fucosylated (BioBet-1554ZP) (CAT#: BioBet-1554ZP) Datasheet

Target
PAD2
Isotype
IgG1
Description
ADCC-Enhanced anti-PAD2 (mAb#2) is a non-fucosylated therapeutic biobetter antibody engineered by Creative Biolabs' Afuco™ technology platform.
Antibody Indication
Rheumatoid Arthritis
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced PAD2 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
PADI2
Full Name
PADI2; peptidyl arginine deiminase, type II; PAD2; PDI2; PAD-H19; protein-arginine deiminase type-2; protein-arginine deiminase type II;
Background
This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2013]
Alternative Names
peptidyl arginine deiminase, type II
Gene ID
11240
Cellular Localization
Cytoplasm
Involvement in Disease
Diseases associated with PADI2 include Multiple Sclerosis and Rheumatoid Arthritis Interstitial Lung Disease.
Related Pathways
Its related pathways are Chromatin organization and Innate Immune System.
Function
Catalyzes the deimination of arginine residues of proteins.
Post-translational modifications
1.Modification sites at neXtProt 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1
Antibody Clone
mAb#2
Host
Mouse
Species Reactivity
Human
Description
The anti-PAD2 antibody are used in the treatment of autoimmune diseases characterized by extracellular citrullination, such as rheumatoid arthritis (RA).
Antibody Indication
Rheumatoid Arthritis

Rheumatoid Arthritis

Related Products

Anti-PAD2 Antibody, Non-Fucosylated (BioBet-1553ZP) (CAT#: BioBet-1553ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

  • *
  • *
  • *
USA

UK

Germany

ISO 9001 Certified - Creative Biolabs Quality Management System.