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Creative Biolabs - ADCC+ Antibody

Anti-Nerve growth factor 2 Antibody, Non-Fucosylated (BioBet-1483ZP) (CAT#: BioBet-1483ZP) Datasheet

Target
Nerve growth factor 2
Isotype
IgG
Description
Anti-Nerve growth factor 2 Antibody, Non-Fucosylated (BioBet-1483ZP) is a human monoclonal IgG antibody against Nerve growth factor 2. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Kidney Cancer; Urinary Bladder Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Nerve growth factor 2 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
NTF3
Full Name
neurotrophin 3
Background
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]
Alternative Names
NTF3; neurotrophin 3; NT3; HDNF; NGF2; NT-3; NGF-2; neurotrophin-3; neurotrophic factor; nerve growth factor 2;
Gene ID
4908
Cellular Localization
Extracellular region or secreted
Involvement in Disease
Diseases associated with NTF3 include Hypochondriasis and Demyelinating Disease.
Related Pathways
Its related pathways are NF-KappaB Family Pathway and Activation of cAMP-Dependent PKA.
Function
Seems to promote the survival of visceral and proprioceptive sensory neurons.
Post-translational modifications
1.Glycosylation at Asn131 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-1483ZP
Host
Human
Species Reactivity
Human
Description
This is antibody against nerve growth factor 2/neurotrophin-3. It can be used as agent for the prophylaxis or treatment of kidney cancer or urinary bladder cancer, and a diagnostic reagent for these cancers.
Antibody Indication
Kidney Cancer; Urinary Bladder Cancer

Kidney Cancer; Urinary Bladder Cancer

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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