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Anti-NaPi2b Antibody, Non-Fucosylated (BioBet-1295ZP) (CAT#: BioBet-1295ZP) Datasheet

Target
NaPi2b
Isotype
IgG1
Description
Anti-NaPi2b Antibody, Non-Fucosylated (BioBet-1295ZP) is a humanized monoclonal IgG1 antibody against NaPi2b. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced NaPi2b antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
SLC34A2
Full Name
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
Background
The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene.
Alternative Names
SLC34A2; solute carrier family 34 (type II sodium/phosphate cotransporter), member 2; NPTIIb; NAPI-3B; NAPI-IIb; sodium-dependent phosphate transport protein 2B; sodium/phosphate cotransporter 2B; type II sodium-dependent phosphate transporter 3b; solute carrier family 34 (sodium phosphate), member 2
Gene ID
10568
Cellular Localization
Membrane
Involvement in Disease
Diseases associated with SLC34A2 include Pulmonary Alveolar Microlithiasis and Testicular Microlithiasis.
Related Pathways
Its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Mineral absorption.
Function
May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli
Post-translational modifications
1.Glycosylation at Asn295, Asn308, Asn313, Asn321, and Asn340 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1
Antibody Clone
BioBet-1295ZP
Host
Humanized
Species Reactivity
Human
Description
The antibody specifically directed against NaPi2b (SLC34A2) are used for treatment of tumors and cancer.
Antibody Indication
Cancer

Cancer

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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