Product Type
Fc Silent Antibody
Description
Anti-Mouse PD-1-Fc silent antibody is derived from clone RMP1-14, which is a Mouse monoclonal antibody targeting the PD-1. And it is intended for the research of Metastatic melanoma, metastatic NSCLC.
Research Area
Cell Biology, Immunology
Antigen Distribution
Biased expression in thymus adult (RPKM 7.6), ovary adult (RPKM 3.5) and 3 other tissues
Disease
Metastatic melanoma, metastatic NSCLC
Size
100 ug
Immunogen
Recombinant Mouse PD-1 protein
Species
Mouse
Clonality
Monoclonal
Clone Number
RMP1-14
Conjugation
Unconjugated
Source
Recombinant
Buffer
PBS, pH 7.4
Application
Block
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
Programmed cell death protein 1
Full Name
Programmed cell death protein 1
Background
PD-1 (Programmed Death-1 receptor) is a key regulator of the threshold of immune response and peripheral immune tolerance. It is expressed on activated T cells, B cells, monocytes, and dendritic cells and binds to PD-L1 or PD-L2.
Alternative Names
Programmed cell death protein 1; Protein PD-1; hPD-1; CD antigen CD279; PDCD1; NACP; PARK1; PARK4; PD1
Gene ID
18566
Uniprot ID
Q02242
