Product Type
Fc Silent Antibody
Description
Anti-Mouse B7-H4-Fc silent antibody is derived from clone 7A1-6, which is a Mouse monoclonal antibody targeting the B7-H4. And it is intended for the research of Autoimmune diseases.
Research Area
Cell Biology, Immunology
Antigen Distribution
Biased expression in kidney (RPKM 5.0), pancreas (RPKM 2.8) and 9 other tissues
Disease
Autoimmune diseases
Size
100 ug
Immunogen
Recombinant Mouse B7-H4 protein
Species
Mouse
Clonality
Monoclonal
Clone Number
7A1-6
Conjugation
Unconjugated
Source
Recombinant
Buffer
PBS, pH 7.4
Application
Block
Application Notes
The use of diluent depends on the detection system used. It is recommended that users test reagents and determine their own optimal dilution.
Handling Advice
This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
Storage Instructions
Product should be stored at -80°C. Repeated freeze and thaw cycles will cause loss of activity. Use product within 24 hours after thawing and keep on ice. Remainder amounts should be aliquoted and immediately re-freezed for future use. Aliquots should never be thawed more than once. Under recommended storage conditions, product is stable for at least one year.
Official Name
V-set domain-containing T-cell activation inhibitor 1
Full Name
V-set domain-containing T-cell activation inhibitor 1
Background
B7-H4, a member of the B7 family of immunoregulatory proteins, inhibits T cell proliferation and cytokine production through ligation of an unknown receptor expressed by activated T cells. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells.
Alternative Names
V-set domain-containing T-cell activation inhibitor 1; T-cell costimulatory molecule B7x; B7-H4; B7h.5; Protein B7S1
Gene ID
79679
Uniprot ID
Q7Z7D3
