Description
Anti-LSR Antibody, Non-Fucosylated (BioBet-1190ZP) is a mouse monoclonal IgG2a antibody against LSR. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Cancer
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced LSR antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
LSR
Full Name
lipolysis stimulated lipoprotein receptor
Alternative Names
LSR; lipolysis stimulated lipoprotein receptor; ILDR3; LISCH7; lipolysis-stimulated lipoprotein receptor; LISCH protein; lipolysis-stimulated remnant; liver-specific bHLH-Zip transcription factor; immunoglobulin-like domain containing receptor 3
Gene ID
51599
Cellular Localization
Plasma membrane
Involvement in Disease
Diseases associated with LSR include Deafness, Autosomal Recessive 42 and Hypotrichosis 1.
Related Pathways
Its related pathways are Lipoprotein metabolism and Glucose / Energy Metabolism.
Function
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity).
Post-translational modifications
1.Ubiquitination at Lys410 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG2a
Antibody Clone
8C8
Description
This antibody specific for LSR molecules are suitable drugs for immunotherapy and treatment of specific cancer.
Antibody Indication
Cancer
