Book a Meeting

Anti-Leukocyte receptor tyrosine kinase Antibody, Non-Fucosylated (BioBet-1194ZP) (CAT#: BioBet-1194ZP) Datasheet

Target
Leukocyte receptor tyrosine kinase
Isotype
IgG
Description
Anti-Leukocyte receptor tyrosine kinase Antibody, Non-Fucosylated (BioBet-1194ZP) is a humanized monoclonal IgG antibody against Leukocyte receptor tyrosine kinase. This product is an ADCC enhanced antibody produced by our Afuco™ platform.
Antibody Indication
Autoimmune Diseases
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced Leukocyte receptor tyrosine kinase antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
LTK
Full Name
leukocyte receptor tyrosine kinase
Background
The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Names
LTK; leukocyte receptor tyrosine kinase; TYK1; leukocyte tyrosine kinase receptor; protein tyrosine kinase 1
Gene ID
4058
Cellular Localization
Membrane
Involvement in Disease
Diseases associated with LTK include Paraphimosis and Systemic Lupus Erythematosus.
Function
A receptor with tyrosine protein kinase activity. The exact function of this protein is unclear. Studies on the chimeric protein (replacement of its extracellular region with several known growth factor receptors, such as EGFR and CSFIR) have shown that it can promote growth, especially neurite growth and cell survival. The signaling pathway seems to involve the pi3k kinase pathway. Participate in the regulation of the endoplasmic reticulum (ER) export sites (ERESs) and the secretory pathway of ER transport to the Golgi apparatus.
Post-translational modifications
1.Glycosylation at Asn257, Asn380, and Asn412 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG
Antibody Clone
BioBet-1194ZP
Host
Humanized
Species Reactivity
Human
Description
The antibody that are immunospecific for LTK are used in the diagnosis, screening, treatment and prophylaxis of ovarian and lung cancer.
Antibody Indication
Autoimmune Diseases

Autoimmune Diseases

Related Products

Anti-Leukocyte receptor tyrosine kinase Antibody, Non-Fucosylated (BioBet-1195ZP) (CAT#: BioBet-1195ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

  • *
  • *
  • *
USA

UK

Germany

ISO 9001 Certified - Creative Biolabs Quality Management System.