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Anti-LAG-3 Antibody, ADCC Enchanced (BioBet-CB-018LX) (CAT#: BioBet-CB-018LX) Datasheet

Target
LAG-3
Isotype
IgG4
Description
Anti-LAG-3 Antibody, ADCC Enchanced (BioBet-CB-018LX) is a glycosylation-modified anti-LAG-3 therapeutic antibody.
Antibody Indication
Chronic lymphocytic leukemia; follicular lymphoma; some types of non-Hodgkin lymphoma (NHL);some non-cancer related illnesses
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced LAG-3 antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
LAG3
Full Name
lymphocyte-activation gene 3
Background
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
Alternative Names
LAG3; lymphocyte-activation gene 3; CD223; lymphocyte activation gene 3 protein
Gene ID
Field of research
Cell Biology, Immunology,
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG4
Antibody Clone
BioBet-CB-018LX
Host
Human
Species Reactivity
Human
Description
ADCC-Enhanced Anti-Human LAG-3 (Relatlimab) Antibody is derived from clone Relatlimab, which is a Human monoclonal antibody with enhanced ADCC activity. Antibody-dependent cellular cytotoxicity (ADCC) is an important function of antibody. It is a part of the humoral immune response to limit and contain infection. The antibody targets the LAG-3, and it is intended for the research of Melanoma.
Antibody Indication
Melanoma

Melanoma

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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