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Anti-KIRD2 subgroup Antibody, Highly Galactosylated (BioBet-GA-338ZP) (CAT#: BioBet-GA-338ZP) Datasheet

Target
KIRD2 subgroup
Isotype
IgG4, κ
Description
Anti-KIRD2 subgroup Antibody, Highly Galactosylated (BioBet-GA-338ZP) is a human IgG4, κ antibody against KIRD2 subgroup which contains with a high level of galactosylation.
Antibody Indication
Acute myeloid leukemia (AML)
Classification
Therapeutic antibody; biobetter

Cooperation Seeking

Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced KIRD2 subgroup antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
KIRD2
Alternative Names
lirilumab;1000676-41-4;IPH 2101;IPH2101;1-7F9;IPH 2102;IPH2102;BMS-986015;Killer-cell immunoglobulin-like receptors;KIRs;KIR2DL1/2/3
Cellular Localization
Plasma membrane
Genecards
6329
Involvement in Disease
Its related pathways are Immune response Role of DAP12 receptors in NK cells and Innate Immune System.
Related Pathways
Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.
Field of research
1.Glycosylation at Asn67, Asn84, Asn144, and Asn178 2.Modification sites at PhosphoSitePlus
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG4, κ
Antibody Clone
BioBet-GA-338ZP
Host
Human
Species Reactivity
Human
Description
Recombinant human monoclonal antibody expressed in CHO binding to human KIRD2 subgroup. Lirilumab is a human monoclonal antibody designed for the treatment of cancer.
Antibody Indication
Acute myeloid leukemia (AML)

Acute myeloid leukemia (AML)

Related Products

Anti-KIRD2 subgroup Antibody, Non-Fucosylated (BioBet-338ZP) (CAT#: BioBet-338ZP)

All products and services are for Research Use Only. Do Not use in humans.

ONLINE INQUIRY

Creative Biolabs has established a team of customer support scientists ready to discuss ADCC/CDC optimization strategies, antibody production, bioinformatics analysis and other molecular biology/biotechnology issues.

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