Description
Anti-IFN alpha Antibody, Highly Galactosylated (BioBet-GA-263ZP) is a humanized IgG1, κ antibody against IFN alpha which contains with a high level of galactosylation.
Antibody Indication
Systemic lupus erythematosus (SLE)
Classification
Therapeutic antibody; biobetter
Cooperation Seeking
Creative Biolabs is interested in collaborating with potential partners (include but not limit to major pharma or biotech firms) to further co-develop ADCC-enhanced IFN alpha antibody. For commercial partners interested in our ADCC-enhanced therapeutic antibodies, Creative Biolabs welcomes collaboration. Here are two ways for your choice, and please contact us for more details.
1) Collaborate with us and co-develop the programs from discovery phase to IND enabling. Costs will be shared.
2) Become a licensed candidate of our programs.
Looking forward to cooperating with you in the near future.
Official Name
IFNA1
Full Name
Interferon Alpha 1
Background
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011]
Alternative Names
Rontalizumab;948570-30-7;rhuMAb IFN alpha;RG7415;IFNA1;interferon, alpha 1;interferon alpha-1/13;IFL;IFN;IFN ALPHA;IFN alpha 1b;IFN alphaD;IFNA13;IFNA@;interferon alpha 1b;leIF D;IFN-alpha 1b;IFN-alpha-1/13;interferon-alpha1;interferon alpha-D;IFN-ALPHA;I
Gene ID
3439
UniProt ID
P01562
Cellular Localization
Extracellular region or secreted
Genecards
5417
Involvement in Disease
Its related pathways are all-trans-Retinoic Acid Mediated Apoptosis and Tuberculosis.
Related Pathways
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Field of research
1.Modification sites at PhosphoSitePlus 2.Modification sites at neXtProt
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Antibody Isotype
IgG1, κ
Antibody Clone
BioBet-GA-263ZP
Description
Recombinant monoclonal antibody to IFN alpha. Rontalizumab is a humanized monoclonal antibody. for treatment of systemic lupus erythematosus.
Antibody Indication
Systemic lupus erythematosus (SLE)
Systemic lupus erythematosus (SLE)
